Palmitoyl Pentapeptide-4

Palmitoyl Pentapeptide-4

Also Known As: Matrixyl, Pal-KTTKS, Formerly Palmitoyl Pentapeptide-3

What is it?

Palmitoyl Pentapeptide-4 is a synthetic peptide composed of five amino acids: lysine, threonine, threonine, lysine, and serine. These amino acids are linked to a 16-carbon aliphatic chain, which enhances the molecule's ability to penetrate the lipid structures of the skin. This peptide is classified as a matrikine, a type of messenger peptide that can regulate cell activities by interacting with specific receptors.

What Makes it Different?

Palmitoyl Pentapeptide-4 is renowned for its ability to stimulate collagen production, which is crucial for maintaining youthful and radiant skin. Unlike other anti-aging ingredients, it offers a high level of skin tolerability, making it suitable for sensitive skin. Studies have shown that it can reduce fine lines and wrinkles significantly, even at very low concentrations.

Where Does it Come From?

This peptide was developed through a collaboration between the French ingredient supplier Sederma and the cosmetics giant Procter & Gamble. It was first introduced to the market in 2000 under the trade name Matrixyl.

Where is it Used?

Palmitoyl Pentapeptide-4 is widely used in anti-aging skincare products, including serums, creams, and eye treatments. Some popular products containing this ingredient include The Ordinary Matrixyl 10% + HA, Olay Regenerist Wrinkle & Pore Vanisher, and Dermadoctor Wrinkle Revenge Rescue And Protect Eye Balm.

Is it Sustainable?

The sustainability of Palmitoyl Pentapeptide-4 is a complex issue. While the peptide itself is synthetic and does not directly deplete natural resources, its production involves several steps that may have environmental impacts. The synthesis of peptides typically requires significant energy and chemical inputs, which can contribute to carbon emissions and chemical waste.

Sustainable Issues Related to its Production

1. Energy Consumption: The production of synthetic peptides like Palmitoyl Pentapeptide-4 is energy-intensive, contributing to greenhouse gas emissions.
2. Chemical Waste: The synthesis process often involves hazardous chemicals, which can result in waste that needs to be carefully managed to avoid environmental contamination.
3. Resource Use: While the peptide itself is synthetic, the raw materials and energy required for its production can strain natural resources.

Efforts are being made to develop greener synthesis methods and to improve the overall sustainability of cosmetic ingredients. However, consumers looking for eco-friendly options should consider these factors when choosing products containing Palmitoyl Pentapeptide-4.